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  • Spine
  • Pain
  • Neural Engineering

Closed-loop & Biomarker-guided Neuromodulation for Spine Related Pain: From Ecaps to Wearables and Remote Monitoring

Part of Closed-Loop & Biomarker-Guided Neuromodulation for Spine Related Pain: From ECAPs to Wearables and Remote Monitoring

Details

Date
Saturday, January 23, 2027
Time
7:00 AM – 8:00 AM
Room
Milano Ballroom I & II
Session type
Breakfast Session
Schedule
See this day

About

Closed-loop neuromodulation is evolving beyond fixed-output stimulation toward biomarker-guided therapy that uses physiologic signals (e.g., ECAPs), motion/posture inputs, patient-reported outcomes, and remote monitoring to improve consistency and durability-particularly in axial low back pain where variability and troubleshooting burden are high. This interactive 50/50 pain-neurosurgery panel will translate closed-loop concepts into real-world decision-making. Pain-focused content will cover phenotype-driven dosing, trial-to-permanent transitions, and how to interpret longitudinal data streams (pain interference, function, sleep/activity, "dose," rescue use) to trigger actionable programming changes. Neurosurgery-focused content will address when changing signals or symptoms reflect lead migration, stenosis progression, hardware issues, or target mismatch, and how to triage to imaging, revision, or alternate targeting. Case vignettes will walk attendees through "data-to-decision" pathways for loss-of-efficacy, overstimulation/undertreatment patterns, and complex post-surgical spines. The session ends with a practical follow-up protocol: what to monitor, thresholds for escalation, team roles, and patient communication strategies that preserve trust while leveraging automation.

Learning objectives

  • Describe major biomarker and closed-loop approaches relevant to spine neuromodulation (e.g., ECAP-based control, motion sensing, remote monitoring inputs).
  • Interpret longitudinal device/patient data to differentiate programming issues from lead/target problems requiring imaging or surgical evaluation.
  • Design a follow-up and escalation protocol that integrates closed-loop/remote monitoring with clear, actionable clinical thresholds.

Faculty

Presentations