- Research & Academics
Neuromodulation for Chronic Abdominal Discomfort Syndrome: Targets, Techniques, and Outcomes
Details
- Date
- Friday, January 22, 2027
- Time
- 10:30 AM – 12:00 PM
- Room
- Milano Ballroom VII & VIII
- Session type
- Concurrent Session
- Schedule
- See this day
About
Chronic Abdominal Discomfort Syndrome (CADS) represents a newly defined clinical entity characterized by persistent abdominal pain without clear structural pathology yet associated with visceral afferent sensitization and central modulation dysfunction. Neuromodulation - targeting DRG (T11-L2), splanchnic nerves, and celiac plexus pathways -offers a promising therapeutic strategy for select phenotypes. However, standardized patient selection, programming strategies, and long-term durability data remain limited. This session provides a structured, phenotype-based approach to visceral neuromodulation.
Learning objectives
- Identify clinical phenotypes of CADS appropriate for neuromodulation trials.
- Describe anatomical targets and procedural considerations for visceral neuromodulation.
- Select waveforms and duty-cycle paradigms optimized for visceral pain and apply structured outcome assessment and troubleshooting algorithms in abdominal neuromodulation.
Faculty
-
Nebojsa Nick Knezevic, MD, PhD
Vice Chair for Research and Clinical Professor
Advocate Illinois Masonic Medical Center and University of Illinois · Chicago, Illinois
-
Mayank Gupta, MD
President & CEO, Associate Professor
Kansas Pain Management / Neuroscience Research Center / Kansas City University · Overland Park, Kansas
-
Mark Malinowski, DO
Interventional Pain Physician
OhioHealth Neurological Physicians · Columbus, Ohio
-
Alaa A. Abd-Elsayed, MD, MBA, MPH
Medical Director
Department of Anesthesiology, University of WI School of Medicine and Public Health · Madison, Wisconsin