Neuromodulation Targets for Chronic Abdominal Pain

Chronic Abdominal Discomfort Syndrome (CADS) represents a newly defined clinical entity characterized by persistent abdominal pain without clear structural pathology yet associated with visceral afferent sensitization and central modulation dysfunction. Neuromodulation - targeting DRG (T11-L2), splanchnic nerves, and celiac plexus pathways -offers a promising therapeutic strategy for select phenotypes. However, standardized patient selection, programming strategies, and long-term durability data remain limited. This session provides a structured, phenotype-based approach to visceral neuromodulation.